That sounds like a wonderful vacation you’ve got planned! It depends on what you mean by the best route from Kona to Hilo—if you’re looking for the fastest way, it will take about an hour and a half if you take this route:
If you’ve got a bit more time on your hands, you can take the long way to Hilo via Hawaii Belt Road and Mamalahoa Highway. This route will take you up the coast and through some wonderful towns full of cafes, delicious food, and shopping opportunities.
There’s a ton to see along your way to Hilo. Check out some of these must-see spots on the Big Island: