2008 Cadillac Escalade transmission replacement usually costs between $4,300 and $4,900 for parts and labor, depending on the mechanic that you use and the quality of the replacement parts.
About $1,000 of that is the cost of labor and the rest is the cost of the new transmission.
Whatever issues you’re having with your transmission, it’s worth checking to see if they can be resolved without replacing the transmission entirely—transmission replacements are rather expensive.